Effects, benefits, and contraindications of cannabidiol (CBD)

By Mitch Rice

The cannabidiol, also known as CBD, is part of the active ingredients commonly found in cannabis Sativa or hemp. Thanks to multiple studies and research, over the years, have been identified over 80 different chemical substances called cannabinoids.

And if THC or tetrahydrocannabinol is, in fact, the prevailing active ingredient in the cannabis extract, cannabidiol still represents a decent 40%.

Today you can legally find and buy the best quality CBD flowers online throughout Europe and the UK.

There are many beneficial effects of CBD. If only a few years ago, the protagonist appeared without a shadow of a doubt THC, thanks to its characteristic psychoactive action, today the scientific community’s attention has focused precisely on the therapeutic potential of cannabidiol. It is because able to effectively treat numerous pathologies without necessarily resorting to pharmacological therapies that are potentially harmful to the body.

Main effects of CBD (cannabidiol)

Cannabidiol or CBD is nothing more than a metabolite of cannabis, an active ingredient that, after undergoing a first particular process of transformation, becomes highly absorbable by the body, which can benefit from the characteristic beneficial effects.

THC, which is responsible for the so-called ” high “, has no psychoactive effect, which means that it does not affect the brain faculties or clarity in any way.

Among the peculiarities of cannabidiol, there is undoubtedly poor water solubility.

It isn’t easy to dissolve it in water. Consequently, it requires fat to promote its solubility, thus making it more assimilable by the body itself. CBD is, in fact, an acid molecule. However, to become more active and therefore qualitatively better, it is necessary to make this molecule neutral through what is commonly called the ” drying process “.

Over the years, it has been understood that the intake of cannabidiol has many positive effects. Through numerous studies and research, it has emerged that it has anti-inflammatory properties. It is perfectly capable of stemming pathologies that were considered irreparable only a few years ago. It appears among the most effective pain-relieving therapies in the treatment of cancer. Furthermore, it is also particularly useful against epilepsy, neurodegenerative diseases such as Alzheimer’s, also rapidly stemming schizophrenia, depression, insomnia, and anxiety states.

The therapeutic use of cannabis has ancient origins: cannabidiol has been used in the medical field for millennia even if, however, around the 1930s, the sale of hemp Sativa was banned mainly for socio-political reasons.

Only recently has the scientific community begun to show a growing interest, investigating its properties in depth and reaching results and discoveries that are certainly noteworthy. It also helped to crumble all the most varied ” urban legends ” that circulate about cannabis through evidence scientific studies that confirm its efficacy and benefits.

In 1973, thanks to some American researchers at Johns Hopkins University, it was discovered that the human brain has an endocannabinoid system, characterized by specific receptors capable of interacting with endocannabinoid substances produced naturally by the body.

These substances are very similar to the cannabinoids commonly found in cannabis. Therefore, it has been shown that the human body has a natural predisposition to the intake of cannabinoids themselves.


The endocannabinoid system tends to be activated spontaneously and in conditions of well-being and pleasure, thus stimulating the immune system.

It promotes relaxation and facilitates digestion and assimilation of nutrients.

It allows you to improve sleep quality and more easily remove any trauma, giving more excellent mental stability and tranquillity to make everyday life more peaceful, permanently, at the expense of stress and common malaise.

Therefore, the human body produces these endocannabinoid substances in a completely natural way, even present in breast milk: they help regulate normal functions related to the nervous system, the cardiovascular system, the immune system, and the reproductive system.

However, in some genetically predisposed subjects, the endocannabinoid system may not work correctly. In this case, the intake of cannabis facilitates the restoration of the body’s natural balance using receptors capable of promoting healing.

Adverse effects of cannabidiol (CBD)

The negative effects due to the intake of cannabidiol are generally not particularly relevant. It has been shown that even with prolonged use at high doses of about 1500 mg per day, cannabidiol is still well tolerated by man, even if it is necessary to pay attention to a series of specific cases.

CDB helps to counteract insomnia by generating a state of overall relaxation. For this reason, it is not advisable to drive after taking it, especially if you are tired or in the evening.

Cannabis intake as interaction is not recommended for drugs that could generate drowsiness, since the same cannabidiol tends to neutralize the activity of some enzymes that help to dispose of some medicines once in the liver.

Cannabidiol also determines a significant lowering of blood pressure: it is, therefore, advisable to avoid its use, especially if you suffer from hypotension or very low blood pressure.

On the other hand, it is recommended for those suffering from hypertension. Similarly, it is better not to abuse it in Parkinson’s, since the cannabinoids could increase the tremors.

If you tend to suffer from dehydration, it is essential to know how CDB causes dry mouth. Although it is not a natural side effect, it is always necessary to replenish fluids after taking cannabis, introducing enough water in such a way as to reduce discomfort.