Eric Dane, the actor known for his roles in Grey’s Anatomy and Euphoria, has died at 53, nearly one year after publicly sharing his diagnosis with amyotrophic lateral sclerosis (ALS). His family confirmed he passed away surrounded by loved ones, including his daughters, Billie Beatrice and Georgia Geraldine.

In the days following his death, friends launched a GoFundMe campaign to help cover medical expenses and support the future needs of his two daughters. The fundraiser notes that Dane remained committed to raising awareness about ALS even as his health declined.

Shortly before his passing, Netflix released Dane’s episode of the documentary series Famous Last Words. The program features interviews recorded with the understanding they will only air after the subject’s death. In his conversation, Dane reflected on his life, career, struggles with addiction and his ALS diagnosis. He also recorded a direct message to his daughters, encouraging them to live fully, pursue their passions, value friendship and face hardship with dignity.

Dane’s ALS advocacy continued after his diagnosis, including efforts to support research and expand access to care. Organizations dedicated to ALS awareness have shared footage and statements highlighting his commitment to advancing treatment and funding initiatives.

He is survived by his daughters and his former spouse, Rebecca Gayheart.