Madonna and Gorillaz opened Music’s Biggest Night with a tech-driven spectacle that blurred the line between live performance and virtual animation at the 2006 Grammys. Gorillaz’ animated members appeared as 3D holograms to perform “Feel Good Inc.” alongside a special appearance from rap legends De La Soul, before Madonna emerged in a dazzling leotard for her global smash “Hung Up.” The collaboration set a new precedent for live music and stands as one of the most memorable Grammy moments of its era. Gorillaz took home the Grammy for Best Pop Collaboration With Vocals for “Feel Good Inc.” that night, and the following year Madonna won Best Electronic/Dance Album for ‘Confessions On A Dance Floor’, the album that gave the world “Hung Up.”