Eric Dane, best known to millions as Dr. Mark “McSteamy” Sloan on Grey’s Anatomy, has died at 53 following a battle with ALS. According to his representatives, Dane passed away at his Beverly Hills home surrounded by his wife Rebecca Gayheart and daughters Billie and Georgia. He publicly shared his diagnosis in April 2025 after first experiencing symptoms in early 2024.
Dane rose to prominence during his eight-season run on Grey’s Anatomy, where his breakout towel-clad introduction became a defining television moment. He later starred as Captain Tom Chandler on TNT’s The Last Ship and as Cal Jacobs on HBO’s Euphoria, continuing to build a career that spanned network television, cable dramas, streaming series and feature films including Marley & Me and X-Men: The Last Stand.
In recent months, Dane had spoken candidly about his health, mobility challenges and determination to keep working. He appeared in the NBC drama Brilliant Minds portraying a firefighter living with ALS and was set to reprise his role in Euphoria’s upcoming season. Colleagues including Patrick Dempsey publicly praised his resilience and courage.
Born in San Francisco, Dane worked steadily in television throughout the 1990s before achieving global fame. Beyond his screen work, he became an advocate for ALS awareness and research. He is survived by his wife Rebecca Gayheart and their two daughters, Billie Beatrice and Georgia Geraldine.